A single-parent family is coined as a family encompassing a single father or a single mother having their dependent child/children. A single-parent family may take its shape in different ways, such as separation, divorce, desertion, and a parent's death. In the middle of the 20th century, most the single-parent families took its shape due to their partner's death. According to Nidhi, Bharti (2009), in the 1970s and 1980s, many single-parent families resulted from separations and divorces. According to Isabel (2014), children raised by single mothers are more likely to underperform in many dimensions, including scholastic achievements and social development, and finally, end up with failure in the labour market. Taken these possible adversities into consideration, the present study explores the quality of life of the adolescent children of single mothers in Kuala Lumpur, Malaysia. This study focuses on Health, Self, Family, Finance, Peers and Schooling among the Adolescents of Single Mothers in Kuala Lumpur, Malaysia. The study will explore the present conditions in-depth and suggest measures to have a healthy Quality of Life. This research will be conducted by exploring a sample of adolescents aged between 13-18. There is no precise data about the adolescent's population (universe) who live in the Kuala Lumpur City of Selangor District. This study will involve Interview schedule and Focus Group Discussions for the data collection. Based on the previous research, it is anticipated that the overall quality of life among the adolescents from single mothers' families would not be great, so their self-esteem and financial credibility are also expected to be low. The magnitude of starvation among adolescents will play a vital role in their quality of life. Compared to the two-parent households in the cityside, adolescents from single-mother families may have a poor lifestyle. Keywords: Quality of Life, Adolescents, Single Mothers, Kuala Lumpur and Educational Institutions